RESUMO
No disponible
Assuntos
Humanos , Masculino , Criança , Doenças Respiratórias/epidemiologia , Doenças Respiratórias/prevenção & controle , Cateterismo , Asma/diagnóstico , Asma/epidemiologia , Albuterol/uso terapêutico , Sensibilidade e Especificidade , Espirometria/tendências , Espirometria , Artéria Pulmonar/patologia , Artéria PulmonarAssuntos
Malformações Arteriovenosas/diagnóstico , Asma/diagnóstico , Pulmão/patologia , Artéria Pulmonar/anormalidades , Infecções Respiratórias/diagnóstico , Animais , Malformações Arteriovenosas/complicações , Malformações Arteriovenosas/patologia , Malformações Arteriovenosas/fisiopatologia , Asma/complicações , Asma/patologia , Asma/fisiopatologia , Criança , Tosse , Diagnóstico Diferencial , Febre , Humanos , Pulmão/diagnóstico por imagem , Angiografia por Ressonância Magnética , Masculino , Artéria Pulmonar/diagnóstico por imagem , Pyroglyphidae/imunologia , Cintilografia , Infecções Respiratórias/etiologia , Infecções Respiratórias/patologia , Infecções Respiratórias/fisiopatologia , Espirometria , Tomografia Computadorizada por Raios XRESUMO
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/clavulanic acid (A-CL) for an infection. Diagnosis was based on the confirmation of an IgE-mediated aetiology by an oral challenge test with amoxicillin-clavulanic acid. Following negative skin test results and CAP for penicilloyl G and V, amoxicillin, ampicillin and cefaclor < 0.35 KU/l, those patients who were allergic to clavulanic acid (positive oral challenge test) were shown to be tolerant to orally-administered Cefuroxime axetil.
Assuntos
Antibacterianos/efeitos adversos , Ácido Clavulânico/efeitos adversos , Hipersensibilidade a Drogas/diagnóstico , Administração Oral , Antibacterianos/imunologia , Criança , Pré-Escolar , Ácido Clavulânico/imunologia , Hipersensibilidade a Drogas/imunologia , Feminino , Humanos , Imunoglobulina E/sangue , Masculino , Estudos Retrospectivos , Testes CutâneosRESUMO
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/clavulanic acid (A-CL) for an infection. Diagnosis was basedon the confirmation of an IgE-mediated aetiology byan oral challenge test with amoxicillin-clavulanic acid. Following negative skin test results and CAP for penicilloy lG and V, amoxicillin, ampicillin and cefaclor< 0.35 KU/l, those patients who were allergic to clavulanic acid (positive oral challenge test) were shown to be tolerant to orally-administered Cefuroximeaxetil
No disponible
Assuntos
Humanos , Masculino , Feminino , Criança , Hipersensibilidade/complicações , Hipersensibilidade/diagnóstico , Ácido Clavulânico/efeitos adversos , Cefuroxima/administração & dosagem , Cefuroxima/uso terapêutico , Testes do Emplastro/métodos , Urticária/induzido quimicamente , Urticária/terapia , Estudos RetrospectivosRESUMO
- Propósito: Valoración de la supervivencia global (SG) y libre de enfermedad (SLE) a 5 años y estudio de los factores pronósticos de los pacientes operados, con finalidad curativa, de adenocarcinoma colorrectal estadios II y III, que recibieron tratamiento adyuvante con 5FU-LEV.- Material y métodos: ciento veintiséis pacientes tratados con esquema 5FU-LEV durante 12 meses, entre septiembre de 1990 y noviembre de 1997.- Resultados: La SG a los 5 años es de 68.3 por ciento y la SLE de 54 por ciento. El número de ganglios afectos por el tumor y la afectación vásculo-linfática y perineural, han resultado factores pronósticos significativos tanto en la SLE como en SG a los 5 años. La existencia de obstrucción intestinal tan sólo resulta factor pronóstico significativo en la SLE a los 5 años.- Conclusiones: los resultados que presentamos son semejantes a otras grandes series conocidas, tanto en supervivencia global y libre de enfermedad como en el estudio univariante de los factores pronósticos. La afectación ganglionar continúa presentando significación pronóstica con el análisis multivariante (AU)
Assuntos
Feminino , Masculino , Humanos , Quimioterapia Adjuvante/métodos , Fluoruracila/administração & dosagem , Levamisol/administração & dosagem , Neoplasias Colorretais/epidemiologia , Intervalo Livre de Doença , Prognóstico , Metástase Linfática , Esquema de Medicação , Estudos Retrospectivos , Neoplasias Colorretais/tratamento farmacológicoRESUMO
OBJECTIVES: To estimate the proportion of interventions in general practice that are based on evidence. DESIGN: A one-year cross-sectional study involving all consultations by patients over age 15 years seen in 34 national primary health care centers. SETTING: The rural Castellon provincial district within the Valencian Community in eastern Spain, with a total population of 21,155 inhabitants. SUBJECTS: of 1990 case histories registered in the course of one year, 4800 consultations were identified; of these, 2341 (49%) distinct diagnosis-intervention pairs were identified and coded. MAIN RESULTS: The evidence basis for the diagnosis-intervention pairs in the study was derived from a computerized search of the scientific literature published in 1992-1996. The quality of the evidence was classified according to the method of Ellis et al. Within the 2341 diagnosis-intervention pairs, there was positive evidence in support of the intervention used in 55%. The evidence basis was sound for 42%, with 38% being based on Type I (clinical trials) evidence and 4% on Type II evidence. The most frequently presenting diseases involved the circulatory (18.7%), respiratory (14.9%), nervous (14.2%), musculo-skeletal (12.5%) and nutrition and metabolism and digestive systems, with 12.1% each. CONCLUSIONS: Clinical practice was clearly supported by positive evidence of all Types (I-III) in a total of 55% of interventions, and by good positive evidence of Type I or II in 42% of interventions. The percentage of evidence-based interventions in general practice serving a substantial population in rural Spain was lower than had been reported by some authors.
